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Updated: Sep 26, 2025
Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
An Unusual TEN-Like Presentation of Juvenile Bullous Pemphigoid: A Diagnostic Challenge
Zahra Nikyar1,2, Parvaneh Hatami1, Zeinab Aryanian1,3
1Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:
Bullous pemphigoid (BP) is an acquired autoimmune bullous disorder rarely seen in the pediatric population. It usually presents as large and tense bullae, predominantly distributed in the acral areas. Herein, we describe a case of childhood BP with an atypical presentation mimicking toxic epidermal necrolysis (TEN). This case shows us that juvenile BP should be considered in the differential diagnosis of TEN in children, particularly if there are unusual features and an intractable course.
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