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Updated: Sep 26, 2025

Rapid Generation of Amyloid from Native Proteins In vitro
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Interconversion between Serum Amyloid A Native and Fibril Conformations.

Fatih Yasar1, Miranda S Sheridan1, Ulrich H E Hansmann1

  • 1Department of Chemistry & Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.

ACS Omega
|April 22, 2022
PubMed
Summary

Serum amyloid A (SAA) overexpression causes amyloidosis. Researchers studied SAA1-76 conversion between folded and fibril states, finding a key salt bridge facilitates fibril formation.

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