Related Experiment Video
Updated: Jul 18, 2026
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Multisystemic Inflammatory Syndrome in Children From the South of Colombia: One Year of Experience
Pilar Pérez López1,2,3, Darling Carvajal Duque1,3, Doris Martha Salgado García3
1Department of Pediatrics, Hospital Universitario Hernando Moncaleano Perdomo, Neiva, Colombia.
Insights
Multisystemic inflammatory syndrome in children (MIS-C) in Colombia predominantly presented with gastrointestinal symptoms. High mortality in these pediatric cases was linked to underlying health issues, necessitating improved physician training for early diagnosis and treatment.
Area of Science:
- Pediatric infectious diseases
- Pediatric critical care
- Epidemiology of viral infections
Background:
- Multisystemic inflammatory syndrome in children (MIS-C) is a severe pediatric complication of COVID-19.
- Limited data exists on MIS-C characteristics in Colombian children.
- This study addresses the knowledge gap regarding MIS-C in this population.
Purpose of the Study:
- To characterize the clinical and epidemiological features of hospitalized children diagnosed with MIS-C in Neiva, Colombia.
- To analyze laboratory findings, cardiac evaluations, treatments, and outcomes.
- To provide insights into MIS-C presentation in a specific South American pediatric cohort.
Main Methods:
- An observational follow-up cohort study was conducted over 12 months (May 2020 - May 2021).
- Data collected included epidemiological, clinical, and laboratory characteristics, echocardiograms, treatments, and outcomes from 34 MIS-C patients.
- Statistical analysis was performed on the collected data.
Main Results:
- The median age of the 34 MIS-C patients was 68 months.
- Gastrointestinal symptoms (vomiting, diarrhea, abdominal pain) were most frequent (79%, 70%, 67%).
- SARS-CoV-2 infection history was documented in 77% of patients; 35.4% showed systolic dysfunction and 35% coronary involvement on echocardiograms.
Conclusions:
- Gastrointestinal manifestations were predominant in Colombian children with MIS-C.
- Mortality was high compared to international data but consistent with Colombian reports, associated with comorbidities.
- Enhanced physician training is crucial for early MIS-C diagnosis and timely intervention.
Background:
Multisystemic inflammatory syndrome in children (MIS-C) is one of the most severe presentations of COVID-19 infection in pediatrics. Currently, we have few studies that describe the characteristics of this condition in Colombian children.
Objective:
To describe the clinical and epidemiological characteristics of children hospitalized with MIS-C in Neiva, Colombia.
Methods:
Observational follow-up study of a cohort of children with MIS-C for 12 months (May 15, 2020, to May 30, 2021) in two hospitals in the city of Neiva. Epidemiological data, clinical characteristics, laboratory characteristics, cardiological evaluation, treatment, and clinical outcomes were analyzed.
Results:
We included 34 patients who met the diagnosis of MIS-C. The median age was 68 months. Some type of nutritional issue was observed by 43.75% of those under 5 years of age and by 27.78% of those over 5 years of age. Gastrointestinal symptoms were the most frequent, with vomiting, diarrhea, and abdominal pain being the most frequent by 79, 70, and 67%, respectively. By 77% of the patients, a history of SARS-COV-2 infection was documented through IgG. In the echocardiogram, 35.4% of the patients had systolic dysfunction, followed by coronary involvement by 35%.
Conclusion:
This study describes a series of cases of children with MIS-C in Colombia. Gastrointestinal manifestations were predominant. Mortality was high in comparison to other countries but similar to that reported in Colombia. This fact was associated with relevant pathological background. More training is required for physicians in order to have a better understanding of the disease so as to have an early diagnosis and timely treatment.
