Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

2.8K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.8K
Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

616
Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:
616
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

2.7K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
2.7K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

2.9K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.9K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

762
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
762
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

2.7K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

KGRD: a knowledge-graph-augmented automated reasoning framework for diagnosis and counselling of paediatric rare genetic disorders.

NPJ digital medicine·2026
Same author

Combined Lingzhi Huang capsules and Zeng Jian health tonic accelerates skin wound healing via BMP5-mediated inhibition of ferroptosis.

Frontiers in immunology·2026
Same author

HECT E3 ubiquitin ligase SMURF2 orchestrates FcεRI-dependent mast cell activation and allergic responses.

The Journal of allergy and clinical immunology·2026
Same author

Association between short-term exposure to atmospheric black carbon and acute exacerbations of childhood asthma.

Frontiers in pediatrics·2026
Same author

Optimizing Mirtazapine Initial Dosing: A Population Analysis of the Effects of BMI, Paroxetine and Fluvoxamine.

Drug design, development and therapy·2026
Same author

Trends in Asthma-Rhinitis Allergic Multimorbidity and Polysensitization in China: The CARRAD Study.

MedComm·2026

Related Experiment Video

Updated: Sep 26, 2025

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

11.1K

Ozone Exposure and Asthma Attack in Children.

Wanting Huang1, Jinzhun Wu1, Xiaoliang Lin2

  • 1Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, China.

Frontiers in Pediatrics
|April 22, 2022
PubMed
Summary
This summary is machine-generated.

Ozone (O3) exposure above 80 μg/m3 increases the risk of asthma attacks in children. Even at lower concentrations, ozone pollution poses a significant threat to pediatric asthma patients.

Keywords:
air pollutionasthma attackcase-crossover designchildozone

More Related Videos

In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
08:54

In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure

Published on: October 22, 2019

9.3K
Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
14:48

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Published on: March 21, 2021

5.2K

Related Experiment Videos

Last Updated: Sep 26, 2025

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

11.1K
In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
08:54

In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure

Published on: October 22, 2019

9.3K
Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
14:48

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Published on: March 21, 2021

5.2K

Area of Science:

  • Environmental Health
  • Pediatric Pulmonology
  • Air Pollution Research

Background:

  • Growing evidence links ozone (O3) exposure to childhood asthma exacerbations.
  • The impact of low-concentration ozone exposure on asthma attacks remains unclear.

Purpose of the Study:

  • To investigate the effects of low-concentration ozone exposure on asthma attacks in children.
  • To determine the threshold concentration of ozone associated with increased asthma risk.

Main Methods:

  • A case-crossover study analyzed 3,475 children with asthma attacks in Xiamen (2016-2019).
  • Conditional logistic regression models assessed associations between asthma attacks and ozone (O3) pollution, considering lag effects.
  • Children were grouped by daily 8-hour maximum average ozone (O3-8 h) levels (<80, 80-99, ≥100 μg/m3).

Main Results:

  • Ozone exposure above 80 μg/m3 significantly increased the risk of acute asthma attacks in children.
  • The association between ozone and asthma attacks was particularly significant at concentrations exceeding 100 μg/m3.
  • This effect was observed consistently across single-pollutant and multi-pollutant models.

Conclusions:

  • Ozone concentrations exceeding 80 μg/m3 are linked to a higher risk of asthma attacks in pediatric populations.
  • Even moderate levels of ozone pollution warrant attention for managing childhood asthma.
  • Findings highlight the importance of air quality monitoring and control for children's respiratory health.