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Related Concept Videos

Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

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Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
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Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

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Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
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Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

1.3K
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

184
Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
184

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Articles linked to this work by shared authors, journal, and citation graph.

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Comparative performance of wearable ECG devices for rhythm monitoring in endurance athletes.

American journal of preventive cardiology·2026
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Association of self-reported sports volume and discipline with atrial arrhythmia prevalence in middle-aged males.

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Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes: a clinical consensus statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the ESC: Part 1-Exercise imaging.

European journal of preventive cardiology·2026
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Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes: a clinical consensus statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the ESC: Part 1-Exercise imaging.

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Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes. A Clinical Consensus Statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology (ESC). Part 2-Cardiovascular Magnetic Resonance, Cardiac CT and Nuclear Imaging.

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Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes: a clinical consensus statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology (ESC), Part 2: Cardiovascular magnetic resonance, cardiac CT, and nuclear imaging.

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Related Experiment Video

Updated: Sep 26, 2025

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
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Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding

Published on: August 30, 2024

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Arrhythmogenic Right Ventricular Cardiomyopathy.

Andrew D Krahn1, Arthur A M Wilde2, Hugh Calkins3

  • 1Center for Cardiovascular Innovation, Heart Rhythm Services, Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada.

JACC. Clinical Electrophysiology
|April 22, 2022
PubMed
Summary

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heart condition involving fibrofatty tissue. Diagnosis and risk stratification are key for managing ARVC patients and preventing sudden cardiac death.

Keywords:
cardiomyopathyinheritedsudden deathventricular arrhythmia

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Area of Science:

  • Cardiology
  • Genetics
  • Pathology

Background:

  • Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a inherited heart muscle disease characterized by fibrofatty replacement of the right ventricular myocardium.
  • While initially described as affecting primarily the right ventricle, biventricular involvement is now recognized.
  • ARVC affects approximately 1:2,000 to 1:5,000 individuals, with a slight male predominance.

Purpose of the Study:

  • To review the current understanding of ARVC, including its diagnosis, risk stratification, and management.
  • To provide clinicians with a practical approach to diagnosing and managing patients with ARVC.

Main Methods:

  • Diagnosis relies on established task force criteria, integrating electrophysiological, imaging, genetic, and histopathologic data.
  • Risk stratification incorporates patient factors such as age, sex, electrophysiological findings, and cardiac imaging results.
  • Management strategies include exercise restriction, pharmacotherapy (e.g., beta-blockers), device implantation (ICD), and catheter ablation.

Main Results:

  • ARVC diagnosis requires a comprehensive assessment using multiple criteria.
  • Risk stratification identifies individuals at high risk for sudden cardiac death and ventricular arrhythmias.
  • Current management focuses on mitigating arrhythmia risk and improving patient outcomes.

Conclusions:

  • ARVC is a complex inherited cardiomyopathy requiring a multidisciplinary diagnostic and management approach.
  • Accurate diagnosis and risk stratification are crucial for effective patient care and prevention of adverse events.
  • Ongoing research continues to refine our understanding and treatment of ARVC.