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Comparative study shows that 1 in 7 Spanish children with COVID-19 symptoms were still experiencing issues after

María Bergia1, Elena Sanchez-Marcos2, Blanca Gonzalez-Haba1

  • 1Pediatrics and Infectious Diseases Department, La Paz University Hospital, Madrid, Spain.

Acta Paediatrica (Oslo, Norway : 1992)
|April 22, 2022
PubMed

Insights

A significant percentage of children experience prolonged symptoms after COVID-19, with older children and those hospitalized at higher risk. This highlights the need for ongoing monitoring and research into long COVID in pediatric populations.

Area of Science:

  • Pediatric Infectious Diseases
  • Public Health

Background:

  • The long-term effects of COVID-19 in children, known as long COVID or post-COVID conditions, are an emerging concern.
  • Understanding the prevalence and risk factors for prolonged symptoms in pediatric populations is crucial for effective management and public health strategies.

Purpose of the Study:

  • To investigate the clinical characteristics and risk factors associated with prolonged symptoms in children following COVID-19 infection.
  • To determine the percentage of children experiencing persistent symptoms and identify predictors of longer symptom duration.

Main Methods:

  • A multicentre retrospective study involving 451 children under 18 with symptomatic COVID-19.
  • Persistent symptoms were assessed via telephone questionnaire, with a control group of 98 children without COVID-19 history included for comparison.

Main Results:

  • 18.4% of children experienced symptoms lasting 4-12 weeks, and 14.6% had symptoms for over 12 weeks.
  • Risk factors for prolonged symptoms included older age (≥5 years), hospitalization, pediatric intensive care unit (PICU) admission, and symptomatic relatives.
  • A notable percentage of the control group also reported prolonged symptoms, particularly older children.

Conclusions:

  • A significant proportion of children develop prolonged symptoms after COVID-19, indicating a substantial public health challenge.
  • Identifying high-risk groups, such as hospitalized children and those with specific demographic factors, is essential for targeted interventions and support.
Abstract

Keywords:
childrenmulticentre studypandemicpost-COVID-19questionnaire

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