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Related Concept Videos

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

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Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
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Healthcare Associated Infections II: Preventive Measures01:22

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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
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Endocarditis I: Introduction01:25

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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Factors Affecting the Risk of Infection01:26

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
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Asepsis01:28

Asepsis

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The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
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Invasive Group A Streptococcus Outbreaks Associated with Home Healthcare, England, 2018-2019.

Laura E Nabarro, Colin S Brown, Sooria Balasegaram

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    Summary
    This summary is machine-generated.

    Healthcare-associated invasive group A Streptococcus (iGAS) outbreaks in England caused 96 cases and 28 deaths. Early detection and interventions are crucial for patient safety and reducing mortality.

    Keywords:
    BacteriaEnglandGroup A StreptococcusStreptococciStreptococcus pyogenesdisease outbreaksinfection controllong-term carepublic healthwhole-genome sequencingwound infection

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    Area of Science:

    • Infectious Diseases
    • Public Health
    • Epidemiology

    Background:

    • Healthcare-associated invasive group A Streptococcus (iGAS) outbreaks are globally prevalent.
    • England uniquely reports outbreaks linked to home healthcare (HHC).

    Purpose of the Study:

    • To describe characteristics of 10 iGAS outbreaks in English home healthcare settings (2018-2019).
    • To evaluate detection methods and control strategies for HHC-associated iGAS.

    Main Methods:

    • Retrospective analysis of 10 iGAS outbreaks.
    • Utilized emm typing and whole-genome sequencing for outbreak detection.
    • Network analysis to identify transmission routes.
    • Screening of home healthcare workers.

    Main Results:

    • 96 iGAS cases and 28 deaths (29% case-fatality rate) occurred across 10 outbreaks.
    • Outbreak duration varied significantly (3-517 days).
    • emm typing and WGS improved outbreak detection; network analysis suggested multiple transmission pathways.
    • Low carriage rate (1/366) found among screened HHC workers.

    Conclusions:

    • iGAS outbreaks in HHC settings are likely underrecognized.
    • Effective interventions and transmission routes require further clarification.
    • Public health awareness of HHC-associated iGAS is vital for patient safety and mortality reduction.