Related Experiment Video
Updated: Sep 26, 2025
Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
Published on: October 20, 2021
Implanted Peroneal Nerve Stimulator Treatment for Drop Foot Caused by Central Nervous System Lesion: A Twelve-Month
Kaare Severinsen1, Kurt Grey2, Anne Haase Juhl3
1Hammel Neurorehabilitation Centre and University Research Clinic, Aarhus University, Denmark. kaarseve@rm.dk.
Objective:
Drop foot is a common impairment following stroke or other causes of central pathology. We report data on patient self-perceived performance, satisfaction with performance, walking ability, and adverse effects after surgical implantation of the ActiGait® drop foot stimulator.
Design:
Prospective case study with a 12-month follow-up.
Subjects:
Twenty-one participants with drop foot caused by central nervous system lesion.
Methods:
The patients' self-perceived performance and satisfaction with performance were evaluated using the Canadian Occupational Performance Measure (COPM). Walking ability was assessed using a 10-m walk test and a 6-min walk. Nerve conduction of the peroneal nerve was examined in 10 patients.
Results:
At follow-up, COPM self-percieved performance from 3.2 to 6.7 points, the median increase being 2.8 (interquartile range (IQR) 2.2-5.0), p < 0.001. Likewise, the COPM satisfaction with performance increased from 2.6 to 6.9 points, the median increase being 4.2 (IQR 2.8-5.8), p < 0.001. Walking velocity increased 0.1 m/s from a baseline measurement of 0.73 m/s (95% confidence interval (95% CI) 0.03-0.2), n = 21, p < 0.01, and walking distance increased by 33 m, from a baseline measurement of 236 m (95% CI 15-51), n = 21, p < 0.001.
Conclusion:
Stimulation of the peroneal nerve by an implantable stimulator increases self-perceived performance, satisfaction with performance, and ambulation in patients with long-lasting drop foot caused by a central nervous system lesion.
