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Updated: Sep 26, 2025

Quantification of Circulating Pig-Specific DNA in the Blood of a Xenotransplantation Model
Published on: September 22, 2020
Clinical xenotransplantation seems close: Ethical issues persist
John W Entwistle1, Robert M Sade2, Daniel H Drake3
1Department of Surgery, Division of Cardiothoracic Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Abstract:
Scientific barriers that have prevented successful xenotransplantation are being breached, yet many ethical issues remain. Some are broad issues that accompany the adoption of novel and expensive technologies, and some are unique to xenotransplantation. Major ethical questions include areas such as: viral transmission; zoonoses and lifetime surveillance; interfering with nature; efficacy, access, and expense; treatment of animals; regulation and oversight.
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