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Related Concept Videos

Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

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Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
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Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

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Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
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Venous Thrombosis III: Interprofessional Care01:29

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Peripheral Artery Disease V: Postoperative Nursing Management01:23

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During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
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Venous Return01:04

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The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
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Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

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The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
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Related Experiment Video

Updated: Sep 26, 2025

Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg
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Improving venous ulcer outcomes.

Laura Bolton1

  • 1Thomas Edison State University, Trenton, New Jersey; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.

Wounds : a Compendium of Clinical Research and Practice
|April 22, 2022
PubMed
Summary

Topical hyaluronic acid (HA) gauze and low-level laser therapy show promise as adjuncts to compression for healing chronic venous leg ulcers (VLUs). Further research is needed to confirm these findings for effective VLU treatment.

Area of Science:

  • Wound healing research
  • Vascular medicine
  • Regenerative medicine

Background:

  • Venous leg ulcers (VLUs) are chronic wounds resulting from impaired venous and lymphatic fluid return.
  • VLUs affect 3-5% of individuals aged 65 and older, with most healing within 12 weeks under compression therapy.
  • Effective VLU management requires addressing venous insufficiency, arterial disease, and utilizing adjunctive therapies.

Purpose of the Study:

  • To review recent randomized clinical trials (RCTs) on adjunctive therapies for venous leg ulcer healing.
  • To evaluate the efficacy of hyaluronic acid (HA) impregnated gauze dressings as an adjunct to compression.
  • To assess the effectiveness of low-level laser radiation as an adjunct to comprehensive VLU treatment protocols.

Main Methods:

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  • Review of recent randomized clinical trials (RCTs) focusing on VLU treatment.
  • Analysis of studies investigating topical hyaluronic acid (HA) gauze versus placebo cream, combined with compression.
  • Examination of trials assessing low-level laser radiation alongside standard VLU care, including compression and lifestyle modifications.

    • Main Results:

    • Hyaluronic acid (HA) impregnated gauze demonstrated potential as an adjunctive therapy for VLU healing.
    • Low-level laser radiation showed promise when used as an adjunct to established VLU management strategies.
    • Results from these RCTs suggest these interventions may improve outcomes beyond standard compression therapy alone.

    Conclusions:

    • Topical hyaluronic acid (HA) and low-level laser therapy represent promising adjunctive treatments for venous leg ulcers.
    • These therapies, when used with appropriate compression and comprehensive care, may enhance VLU healing rates.
    • Further investigation into the optimal application and long-term effects of these adjunctive VLU treatments is warranted.