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Updated: Sep 26, 2025

Generation of RNA/DNA Hybrids in Genomic DNA by Transformation using RNA-containing Oligonucleotides
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Arabinonucleic acids containing C5-propynyl modifications form stable hybrid duplexes with RNA that are efficiently

Alexander Pontarelli1, Christopher J Wilds1

  • 1Department of Chemistry and Biochemistry, Faculty of Arts and Science, Concordia University, 7141 Rue Sherbrooke Ouest, Montréal, Québec H4B 1R6, Canada.

Bioorganic & Medicinal Chemistry Letters
|April 22, 2022
PubMed

Keywords:
Arabino nucleic acidsC5-propynyl nucleosidesE. coli RNase HModified oligonucleotidesNuclease stability

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