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Environmental lead exposure and its correlation with intelligence quotient level in children
Pushkar Singh Rawat1, Shalini Singh1, Abbas Ali Mahdi2
1Department of Biochemistry, University of Lucknow, Lucknow 226007, Uttar Pradesh, India.
Lead poisoning in children significantly impacts intelligence quotient (IQ) and neurobehavioral capabilities. Lower socioeconomic status and certain environmental factors are linked to higher blood lead (BL) levels, underscoring the need for targeted interventions.
Area of Science:
- Environmental Health
- Pediatric Neurotoxicology
- Public Health
Background:
- Lead (Pb) is a ubiquitous neurotoxicant causing cognitive impairment and health issues globally.
- Childhood lead exposure remains a significant public health concern, particularly in developing nations.
- Understanding the link between lead poisoning, sociodemographic factors, and cognitive function in children is crucial.
Purpose of the Study:
- To investigate the relationship between blood lead (BL) levels and sociodemographic status in children.
- To assess the impact of lead exposure on the intellectual and neurobehavioral capabilities of children.
- To determine correlations between lead levels, cognitive function, and environmental factors.
Main Methods:
- Blood lead (BL) levels were measured in 43 children (aged 4-12) using anodic stripping voltammetry (ASV).
- Intelligence quotient (IQ) was assessed using the Goodenough draw-A-person test.
- Sociodemographic data, including socioeconomic status and environmental exposures, were collected via questionnaires.
Main Results:
- Mean BL level was 19.93 ± 9.22 μg/dL, with higher levels associated with low social status, maternal employment, and increased time spent outdoors.
- Significant correlations were found between BL levels and water source, age, house type, and kohl use.
- IQ levels decreased in a concentration-dependent manner, showing a strong negative correlation with BL levels (r = -0.963, p < 0.01).
Conclusions:
- Blood lead (BL) levels are significantly associated with reduced IQ levels in children.
- Sociodemographic characteristics are identified as risk factors influencing children's BL levels.
- Lead exposure adversely affects children's learning, memory, and intelligence quotient, with effects inversely proportional to BL levels.
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