Genetic study with 21 autosomal STRs in five Peruvian macro regions for human identification purposes

Area of Science:

• Forensic genetics
• Population genetics

Background:

• Population-specific genetic data is crucial for accurate forensic DNA profiling.
• Understanding genetic variation within Peru is essential for establishing reliable forensic statistics.

Purpose of the Study:

• To analyze genetic variation across five Peruvian macro regions.
• To evaluate the suitability of population-specific genetic data for forensic applications.

Main Methods:

• Analysis of 1541 DNA samples from five Peruvian regions.
• Typing of 21 autosomal Short Tandem Repeat (STR) loci and one amelogenin marker using Investigator 24 plex kits.
• Calculation of combined power of discrimination and combined probability of exclusion.

Main Results:

• High combined power of discrimination (0.9999999999) and combined probability of exclusion (0.99999978) were observed.
• Genetic profiles across different Peruvian geographic subgroups showed similarity.
• The data supports the use of combined Peruvian population statistics for forensic casework.

Conclusions:

• The genetic data from Peruvian population subgroups are sufficiently similar for consolidated use in forensic casework.
• This study provides valuable population genetic data for Peruvian forensic investigations.