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Updated: Sep 26, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

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Population Pharmacokinetic Model of Piperacillin in Critically Ill Patients and Describing Interethnic Variation

Cristina Sanches1, Geisa C S Alves1, Andras Farkas2

  • 1Campus Centro Oeste, Universidade Federal de Sao Joao del Rei, Divinopolis 35501-296, Brazil.

Antibiotics (Basel, Switzerland)
|April 23, 2022
PubMed
Summary

This study developed a piperacillin population pharmacokinetic model for critically ill Brazilian patients. Dose adjustments based on creatinine clearance are recommended for optimal treatment outcomes.

Keywords:
antimicrobialcritically illethnic grouppharmacokineticspiperacillin

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