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Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis I01:29

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis III01:31

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Chronic Pharyngitis01:23

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Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
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Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
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Pulmonary Tuberculosis V01:28

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Endocarditis II: Clinical Features of Infective Endocarditis01:25

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Granulomatous Cheilitis or Tuberculid?

Georgi Tomov1, Parvan Voynov2, Svitlana Bachurska3

  • 1Department of Periodontology and Oral Mucosa Diseases, Faculty of Dental Medicine, Medical University of Plovdiv, 15-A "Vasil Aprilov" Blvd, 4002 Plovdiv, Bulgaria.

Antibiotics (Basel, Switzerland)
|April 23, 2022
PubMed
Summary
This summary is machine-generated.

Granulomatous cheilitis (GC) can be a lip manifestation of tuberculosis. This case study shows successful treatment of GC due to a tuberculid using Isoniazid monotherapy in an immunocompetent patient.

Keywords:
IGRATSTantibiotic treatmentgranulomatous cheilitistuberculid

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Immunology

Background:

  • Granulomatous cheilitis (GC) is a lip disorder with diverse causes, including infections.
  • Mycobacterium tuberculosis (MBT) infection is a potential secondary cause of GC.
  • GC can present as a tuberculid, a hypersensitivity reaction to tuberculosis.

Observation:

  • An immunocompetent patient presented with GC.
  • The patient was diagnosed with GC secondary to a tuberculid.
  • The underlying cause was presumed to be tuberculosis.

Findings:

  • The patient showed a positive response to Isoniazid monotherapy.
  • Isoniazid effectively treated the granulomatous inflammation of the lips.

Implications:

  • This case highlights the importance of considering tuberculosis in GC etiology.
  • Isoniazid monotherapy may be a viable treatment option for GC-associated tuberculids.
  • Early diagnosis and treatment of underlying tuberculosis are crucial for managing this condition.