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The intersex baby.

R J Lilford, P R Dear

    British Journal of Hospital Medicine
    |January 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    About 1 in 2000 newborns experience ambiguous genitalia, a condition where the external appearance is unclear. This article reviews intersex disorders, focusing on chromosomal and endocrine diagnostic methods.

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    Area of Science:

    • Pediatric Endocrinology
    • Genetics
    • Reproductive Medicine

    Background:

    • Ambiguous genitalia affect approximately 1 in 2000 live births.
    • The degree of genital ambiguity does not predict the specific cause.
    • Intersex variations encompass a spectrum of conditions affecting sexual development.

    Purpose of the Study:

    • To discuss intersex disorders in newborns.
    • To highlight the importance of chromosomal and endocrine investigations.
    • To provide an overview of diagnostic approaches for ambiguous genitalia.

    Main Methods:

    • Review of intersex disorders.
    • Emphasis on chromosomal analysis.
    • Focus on endocrine function tests.

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    Main Results:

    • The etiology of ambiguous genitalia is diverse and not indicated by the physical presentation.
    • Chromosomal and endocrine evaluations are crucial for diagnosis.
    • A systematic investigation is necessary for appropriate management.

    Conclusions:

    • Accurate diagnosis of intersex conditions relies on comprehensive genetic and endocrine assessments.
    • Early and precise diagnosis is vital for appropriate medical and psychosocial care.
    • Further research into the underlying mechanisms of intersex variations is warranted.