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Adalimumab in Treating Refractory Livedoid Vasculopathy
Xiao-Wen Huang1, Huan-Xin Zheng1, Meng-Lei Wang1
1Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou 510150, China.
Abstract:
Livedoid vasculopathy is a chronic, recurrent skin disorder. It seriously affects the quality of patients' life. However, the pathogenesis has not been fully identified yet. Here, this retrospective study describes the successful use of anti-TNF-α agent adalimumab in three cases of refractory livedoid vasculopathy, which has not been reported previously. In addition, we provide some clinical evidence that adalimumab therapy is efficient in improving skin lesions and relieving the pain of livedoid vasculopathy.
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