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Prevention and Treatment of Oral Complications in Hematologic Childhood Cancer Patients: An Update
Alba Ferrández-Pujante1, Amparo Pérez-Silva1,2, Clara Serna-Muñoz1,2
1Department of Integral Paediatric Dentistry, Faculty of Medicine and Dentistry, University of Murcia, 30008 Murcia, Spain.
Insights
This study outlines essential oral care protocols for children undergoing cancer treatment. Implementing these strategies minimizes oral health complications and treatment side effects in pediatric cancer patients.
Area of Science:
- Oncology
- Pediatric Dentistry
- Oral Medicine
Background:
- Cancer significantly impacts children's quality of life.
- Paediatric cancer patients require tailored oral care throughout their treatment phases.
Purpose of the Study:
- To update existing research on optimal oral care for children diagnosed with cancer.
- To define evidence-based interventions for maintaining oral health in this vulnerable population.
Main Methods:
- Comprehensive literature search across multiple databases (PubMed, Cochrane, Scopus, etc.) and hospital websites.
- Inclusion of 114 articles and two hospital protocols for review.
- Categorization of interventions into three distinct phases of cancer treatment.
Main Results:
- Phase I (Pre-treatment): Medical record review, oral history, and planning preventive strategies and dental treatments.
- Phase II (During/Post-chemo-radiotherapy): Oral hygiene maintenance, patient/parent education, and management of treatment-related complications.
- Phase III (Long-term): Periodic check-ups, ongoing oral hygiene reinforcement, dental treatments, and symptomatic care for long-term effects.
Conclusions:
- Standardized oral care protocols are crucial for pediatric cancer patients.
- Proactive management can prevent or minimize oral complications and side effects of cancer therapies.
Abstract:
Cancers have a highly negative impact on the quality of life of paediatric patients and require an individualised oral treatment program for the phases of the disease. The aim of this study was to update existing research on oral care in children diagnosed with cancer. We carried out a literature search (in English, Spanish and Portuguese) in the Pubmed, Cochrane Library, EBSCO, WOS, SciELO, Lilacs, ProQuest, and SCOPUS databases and the websites of hospitals that treat childhood cancers. We found 114 articles and two hospital protocols. After review, we describe the interventions necessary to maintain oral health in children with cancer, divided into: phase I, before initiation of cancer treatment (review of medical record and oral history, planning of preventive strategies and dental treatments); phase II, from initiation of chemo-radiotherapy to 30-45 days post-therapy (maintenance of oral hygiene, reinforcement of parent/patient education in oral care, prevention and treatment of complications derived from cancer treatment); phase III, from 1 year to lifetime (periodic check-ups, maintenance, and reinforcement of oral hygiene, dental treatments, symptomatic care of the effects of long-term cancer treatment). The use of standardised protocols can avoid or minimise oral cancer complications and the side effects of cancer therapies.
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