Prevention and Treatment of Oral Complications in Hematologic Childhood Cancer Patients: An Update

Alba Ferrández-Pujante1, Amparo Pérez-Silva1,2, Clara Serna-Muñoz1,2

  • 1Department of Integral Paediatric Dentistry, Faculty of Medicine and Dentistry, University of Murcia, 30008 Murcia, Spain.

Insights

This study outlines essential oral care protocols for children undergoing cancer treatment. Implementing these strategies minimizes oral health complications and treatment side effects in pediatric cancer patients.

Area of Science:

  • Oncology
  • Pediatric Dentistry
  • Oral Medicine

Background:

  • Cancer significantly impacts children's quality of life.
  • Paediatric cancer patients require tailored oral care throughout their treatment phases.

Purpose of the Study:

  • To update existing research on optimal oral care for children diagnosed with cancer.
  • To define evidence-based interventions for maintaining oral health in this vulnerable population.

Main Methods:

  • Comprehensive literature search across multiple databases (PubMed, Cochrane, Scopus, etc.) and hospital websites.
  • Inclusion of 114 articles and two hospital protocols for review.
  • Categorization of interventions into three distinct phases of cancer treatment.

Main Results:

  • Phase I (Pre-treatment): Medical record review, oral history, and planning preventive strategies and dental treatments.
  • Phase II (During/Post-chemo-radiotherapy): Oral hygiene maintenance, patient/parent education, and management of treatment-related complications.
  • Phase III (Long-term): Periodic check-ups, ongoing oral hygiene reinforcement, dental treatments, and symptomatic care for long-term effects.

Conclusions:

  • Standardized oral care protocols are crucial for pediatric cancer patients.
  • Proactive management can prevent or minimize oral complications and side effects of cancer therapies.

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