Related Experiment Video
Updated: Sep 26, 2025

Chronic Social Defeat Stress in Early Adolescent Male Mice
Published on: January 24, 2025
Association between Childhood Maltreatment and Suicidal Ideation: A Path Analysis Study
Isabella Berardelli1, Salvatore Sarubbi2, Elena Rogante3
1Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Centre, Sant'Andrea Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Via di Grottarossa 1035, 00189 Rome, Italy.
Childhood maltreatment, including sexual abuse, emotional abuse, and neglect, significantly increases suicidal ideation in adults. Dissociative symptoms and hopelessness act as key mediators in this relationship, highlighting the need for early intervention.
Area of Science:
- Psychiatry and Mental Health
- Childhood Trauma Research
- Suicidology
Background:
- Childhood maltreatment is a known risk factor for adverse mental health outcomes.
- Previous research suggests a link between maltreatment, suicidal ideation, dissociative symptoms, and hopelessness.
- The specific pathways through which different types of maltreatment influence suicidal ideation require further elucidation.
Purpose of the Study:
- To examine the direct and indirect effects of various types of childhood maltreatment on suicidal ideation in adult psychiatric inpatients.
- To investigate the mediating roles of dissociative symptoms and hopelessness in the relationship between childhood maltreatment and suicidal ideation.
- To utilize path analysis to model these complex relationships.
Main Methods:
- A sample of 215 adult psychiatric inpatients was recruited.
- Data were collected using validated instruments: Childhood Trauma Questionnaire (CTQ), Beck Hopelessness Scale (BHS), Dissociative Experiences Scale (DES-II), and Columbia-Suicide Severity Rating Scale (C-SSRS).
- Path analysis was employed to test the proposed mediation model.
Main Results:
- Sexual abuse directly predicted increased suicidal ideation (β = 0.18, p < 0.05).
- Emotional abuse and neglect indirectly increased suicidal ideation through dissociation (β = 0.05) and hopelessness (β = 0.10).
- Both dissociation and hopelessness were significant mediators in the pathway from emotional abuse/neglect to suicidal ideation.
Conclusions:
- Childhood maltreatment, particularly sexual abuse, is a significant direct predictor of suicidal ideation.
- Emotional abuse and neglect contribute to suicidal ideation indirectly via their effects on dissociative symptoms and hopelessness.
- Clinical awareness and screening for childhood maltreatment are crucial for assessing and managing suicide risk in adult psychiatric populations.
Related Concept Videos
Psychological and Sociocultural Causes of Schizophrenia
Bullying
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Relationship with Parents: Attachment
Theory of Romantic Attachment in Adulthood
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...

