[Biological and hematochemical characteristics of herbivorous common voles (Microtus arvalis Pallas)]

In 1979, some pairs of voles (Microtus arvalis Pallas) were introduced to our laboratory from Hungary. Thereafter, they were successfully bred and increased in number, as experimental small animals for herbivorous domestic animals. They have been raised in a room and fed with pelleted feed for herbivores and chopped hay-cubes. We can change the high-fiber-containing rations from the chopped hay-cube to the alfalfa pellet that is widely available in laboratories. Regarding the breeding characteristics of the voles, the average litter size was 5.44 +/- 1.64, and the age at the first birth was 55.4 +/- 10.7 days. Some voles with white coats were found during the breeding process in our laboratory. Hematochemical characteristics of the voles were determined and the following characteristics were noted. Red blood cell counts of the voles were higher than those of other experimental animals (rat, mouse). White blood cell counts of the voles were lower than those of the other animals. The electrophoretic patterns of serum protein differed markedly from those of other experimental animals. The gamma-globulin concentrations of the voles were very low, and A/G ratios were high. Blood glucose concentrations of the voles were lower than those of the other mono-gastric experimental animals. Activities of serum enzymes (GOT, GPT, ALP) were higher than those of other experimental animals (rat, mouse, cow).