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Updated: Aug 14, 2026

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model
08:46

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model

Published on: September 29, 2011

Genetic instability as the primary cause of human aging

B L Strehler

    Experimental Gerontology
    |January 1, 1986
    PubMed
    Summary

    Aging results from an evolved balance between damaging events and protective effects. Human aging is linked to DNA damage, specifically gene loss, not classical mutations, driven by unique evolutionary pressures.

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