Covalent Organic Frameworks for Chemical and Biological Sensing
Shiji Zhang1, Danqing Liu1, Guangtong Wang2
1School of Material Science and Chemical Engineering, Harbin University of Science and Technology, Harbin 150080, China.
Molecules (Basel, Switzerland)
|April 23, 2022
Summary
Covalent organic frameworks (COFs) offer precise sensing capabilities due to their ordered pores. This review explores COF applications in detecting gases, ions, and biomolecules, highlighting future trends and challenges.
Area of Science:
- Materials Science
- Chemistry
- Nanotechnology
Background:
- Covalent organic frameworks (COFs) are crystalline porous polymers with ordered structures and tunable pores.
- Since 2005, COFs have been synthesized with diverse structures for applications in gas storage, catalysis, and optoelectronics.
- COFs show promise in chemical and biological sensing due to selective analyte adsorption and detectable property changes.
Purpose of the Study:
- To review the fundamental principles of COF-based chemical and biological sensing.
- To summarize the applications of COFs in detecting various substances like gases, ions, organic compounds, and biomolecules.
- To discuss current trends and challenges in the field of COF-based sensing.
Main Methods:
- Review of existing literature on COF synthesis and applications in sensing.
- Analysis of the mechanisms underlying COF-based detection of analytes.
- Categorization of COF sensing applications based on target analytes.
Main Results:
- COFs' ordered pores facilitate selective adsorption and detection of target molecules.
- COFs have demonstrated effectiveness in sensing gases, ions, organic compounds, and biomolecules.
- The interaction between analytes and COF frameworks can induce measurable optical or electrical signal changes.
Conclusions:
- COF-based sensing leverages unique structural and electronic properties for high sensitivity and selectivity.
- Further research is needed to address challenges and unlock the full potential of COFs in diverse sensing applications.
- COFs represent a promising platform for developing advanced chemical and biological sensors.
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