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Updated: Sep 26, 2025

Noninvasive In Vivo Small Animal MRI and MRS: Basic Experimental Procedures
Published on: October 20, 2009
Clinical experience with an in-NICU magnetic resonance imaging system
Kirsten R Thiim1, Elizabeth Singh1, Srinivasan Mukundan2,3
1Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Objective:
To evaluate the utility of the 1 Tesla (1 T) Embrace (Aspect Imaging) neonatal magnetic resonance imaging (MRI) scanner in a level III NICU.
Study Design:
Embrace brain MRI findings for 207 infants were reviewed, including 32 scans directly compared within 5 days with imaging on a 3 T Siemens Trio. Clinical MRI scan abnormalities were also compared to cranial ultrasound findings.
Result:
Of the 207 Embrace brain MRIs, 146 (70.5%) were obtained for clinical indications and 61 (29.5%) were research cases. Abnormal findings were found in 80 scans, most commonly hemorrhage and white matter injury. Notable findings included a stroke, medullary brainstem tumor, and polymicrogyria. In the 1 T versus 3 T comparison cohort, results were discordant in only one infant with punctate foci of susceptibility noted only on the 3 T scan.
Conclusion:
The Embrace MRI scans detected clinically relevant brain abnormalities and in a subset were clinically comparable to 3 T scans.
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