Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

8.0K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
8.0K
Bone Disorders01:29

Bone Disorders

4.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
4.0K
Standards of Care II01:19

Standards of Care II

733
Nurses bear specific legal responsibilities under several federal statutes, including:
733

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Inflammatory Biomarkers Prognostic Index (IBPI) obtained from standard preoperative blood tests predicts postoperative complications in patients undergoing pelvic exenteration for locally recurrent rectal cancer.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same author

Mutation type, tyrosine kinase function in normal cell and tyrosine kinase inhibitor activity in cancers.

Scientific reports·2026
Same author

Doubting T(h)OMAS: has the era of precision oncology arrived in uterine leiomyosarcoma?

Annals of oncology : official journal of the European Society for Medical Oncology·2026
Same author

Prediction of Mutations and Outcome in Gastrointestinal Stromal Tumors with Deep Learning: A Multicenter, Multinational Study.

medRxiv : the preprint server for health sciences·2026
Same author

Activity of chemotherapy in mesenchymal chondrosarcoma: a multicentre retrospective analysis within the Italian Sarcoma Group network.

ESMO open·2026
Same author

International multicenter retrospective study on pleomorphic rhabdomyosarcoma (P-RMS), a PUSH platform study: outcome of primary localized disease.

ESMO open·2026
Same journal

DNA polymerase epsilon catalytic subunit (POLE) in cancer: implications for tumor biology and therapeutic strategies - a comprehensive review.

Critical reviews in oncology/hematology·2026
Same journal

Long Non-Coding RNAs in Triple-Negative Breast Cancer: Emerging Drivers of Tumor Biology, Prognosis, and Drug Resistance.

Critical reviews in oncology/hematology·2026
Same journal

Alternative Splicing in Breast Cancer Drug Resistance: Mechanisms, Therapeutic Targeting, and Clinical Translation.

Critical reviews in oncology/hematology·2026
Same journal

Gene Fusions in Non-small cell lung carcinoma (NSCLC): Expert Perspectives and Practical Considerations for routine testing.

Critical reviews in oncology/hematology·2026
Same journal

Opportunities and Challenges of Dihydrodiol dehydrogenase Expression in Hepatocellular carcinoma.

Critical reviews in oncology/hematology·2026
Same journal

Ferroptosis in glioblastoma: Molecular determinants, immune crosstalk, and therapeutic opportunities.

Critical reviews in oncology/hematology·2026
See all related articles

Related Experiment Video

Updated: Sep 26, 2025

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
09:25

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

19.3K

SELNET clinical practice guidelines for bone sarcoma.

J Y Blay1, E Palmerini2, J Bollard1

  • 1Léon Bérard Center, 28 rue Laennec 69373 Lyon Cedex 08, France.

Critical Reviews in Oncology/Hematology
|April 23, 2022
PubMed
Summary
This summary is machine-generated.

Bone sarcomas are rare cancers requiring expert multidisciplinary care. These clinical practice guidelines provide a standard approach for diagnosis, treatment, and follow-up of bone sarcoma patients in Latin America.

Keywords:
Bone sarcomaClinical guidelinesLatin-America context

More Related Videos

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

7.3K
Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

14.5K

Related Experiment Videos

Last Updated: Sep 26, 2025

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
09:25

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

19.3K
Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

7.3K
Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

14.5K

Area of Science:

  • Oncology
  • Orthopaedic Surgery
  • Medical Genetics

Background:

  • Bone sarcomas are rare adult neoplasms (<0.2% of all cases).
  • Heterogeneity and low frequency necessitate specialized multidisciplinary management.
  • Multidisciplinary tumor board discussions improve patient outcomes.

Purpose of the Study:

  • To establish standard clinical practice guidelines for bone sarcoma care in Latin America.
  • To improve clinical outcomes for sarcoma patients through a collaborative network.
  • To provide a comprehensive approach to diagnosis, treatment, and follow-up.

Main Methods:

  • Development of Clinical Practice Guidelines (CPG) by a multidisciplinary expert group.
  • Consensus agreement among specialists from the Sarcoma European Latin-American Network (SELNET).
  • Inclusion of medical oncologists, radiation oncologists, surgical oncologists, orthopaedic surgeons, radiologists, pathologists, molecular biologists, and patient advocates.

Main Results:

  • The guidelines offer a standard approach for bone sarcoma management.
  • Emphasis on multidisciplinary care within reference centers.
  • Focus on improving patient outcomes in the Latin-American context.

Conclusions:

  • Multidisciplinary management is essential for optimizing bone sarcoma patient outcomes.
  • The SELNET CPG provides a framework for standardized bone sarcoma care in Latin America.
  • These guidelines aim to enhance sarcoma care delivery and patient outcomes across the region.