Related Experiment Videos
The kidney in hematologic disease. A review
The International Journal of Pediatric Nephrology
|October 1, 1986
Summary
This review highlights the kidney's role in systemic diseases and details its involvement in hematologic conditions like sickle cell anemia and leukemia, emphasizing coagulation
Area of Science:
- Nephrology
- Hematology
- Pathophysiology
Background:
- The kidney is implicated in numerous systemic conditions, including collagen, endocrine, liver, infectious, neoplastic, and cardiac diseases, as well as pregnancy.
- Renal involvement in hematologic diseases is often underemphasized.
Purpose of the Study:
- To review the role of coagulation in the pathophysiology of renal disease.
- To present the spectrum of renal involvement in various hematologic diseases.
Main Methods:
- Literature review focusing on coagulation and renal pathophysiology.
- Summarization of renal manifestations in specific hematologic disorders.
Main Results:
- Coagulation plays a significant role in the development of renal disease.
- Specific hematologic diseases with notable renal impact include sickle cell anemia, hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, and leukemia.
Conclusions:
- Hematologic diseases represent a critical, often overlooked, category of systemic conditions affecting the kidney.
- Understanding the interplay between coagulation and renal pathology is crucial for managing these complex cases.