Related Experiment Video

Updated: Sep 26, 2025

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

17.4K

A clinico-radiological study of deep cerebral venous thrombosis

Jayantee Kalita1, Abhishek Sachan2, Ashish K Dubey2

  • 1Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli, Lucknow, Uttar Pradesh, 226014, India. jayanteek@yahoo.com.

Neuroradiology
|April 25, 2022
PubMed

Insights

Isolated deep cerebral venous thrombosis (DCVT) is rare. While additional sinus thrombosis presents more severe illness and higher mortality, long-term outcomes for survivors are similar in both isolated DCVT and combined cases.

Area of Science:

  • Neurology
  • Radiology
  • Vascular Medicine

Background:

  • Deep cerebral venous thrombosis (DCVT) can occur in isolation or with concurrent sinus thrombosis.
  • Understanding the distinct clinical and radiological profiles of isolated DCVT versus DCVT with sinus involvement is crucial for patient management.

Purpose of the Study:

  • To compare the clinical and radiological findings and outcomes of patients with isolated DCVT against those with DCVT and additional sinus thrombosis.

Main Methods:

  • A cohort of 41 patients diagnosed with DCVT via MR venography was divided into two groups: isolated DCVT (Group A) and DCVT with additional sinus thrombosis (Group B).
  • Clinical features, risk factors, MRI findings, and outcomes at 1, 3, and 6 months were analyzed and compared between the groups.

Main Results:

  • Group B patients (with sinus thrombosis) exhibited a shorter illness duration, more frequent vomiting, and higher rates of papilledema.
  • While Group A (isolated DCVT) showed more frequent thalamic and basal ganglia lesions on MRI, Group B had higher mortality at 1 month.
  • Good outcomes were observed in 50% of Group A and 60.6% of Group B at 1 month, improving to 62.5% and 80.6% respectively by 3 months, with negligible further improvement.

Conclusions:

  • Isolated DCVT is an uncommon presentation.
  • The presence of additional sinus thrombosis in DCVT cases is associated with more severe clinical presentation and increased mortality.
  • Despite initial differences in severity and short-term outcomes, long-term prognoses for survivors are comparable between isolated DCVT and DCVT with sinus thrombosis.
Abstract

Keywords:
Cerebral venous thrombosisMR venographyMRIOutcomeRisk factorStraight sinus

More Related Videos

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli13:10

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli

Published on: September 25, 2016

10.0K
A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage08:12

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage

Published on: July 28, 2018

8.2K

Related Concept Videos

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
49
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
34
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
49
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
36
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
79
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
80