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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

708
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
708
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

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Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
76
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

187
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
187
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

60
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
60
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

518
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
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A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
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Acute amebic appendicitis in early pregnancy.

Monika Aggarwal1, Sanjay Sharma2, Rohit Tewari3

  • 1Classified Specialist (Pathology), Base Hospital, Delhi Cantt., India.

Medical Journal, Armed Forces India
|April 25, 2022
PubMed
Summary
This summary is machine-generated.

Intestinal parasitic infections are a global health concern, particularly in India. This case report details rare acute amoebic appendicitis, emphasizing thorough histopathology and combined surgical and antimicrobial treatment.

Keywords:
Acute appendicitisEntamoeba histolyticaHematophagous trophozoitesTrophozoites

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Pathology

Background:

  • Intestinal parasitic infections represent a significant global health burden, disproportionately affecting developing nations like India.
  • These infections are a leading cause of morbidity and mortality worldwide.
  • Acute amoebic appendicitis is an uncommon clinical presentation.

Observation:

  • A case of acute appendicitis in a young pregnant woman was identified.
  • Histopathological examination revealed Entamoeba histolytica trophozoites within the appendix's mucosal epithelium and submucosal layers.
  • The appendix showed marked signs of acute inflammation.

Findings:

  • The appendix was infected with Entamoeba histolytica, leading to acute appendicitis.
  • The presence of amoebic trophozoites confirmed the parasitic origin of the appendicitis.

Implications:

  • Thorough histopathological examination of the appendix at multiple levels is crucial for diagnosing rare conditions like amoebic appendicitis.
  • Combined treatment involving appendicectomy and antimicrobial therapy is recommended.
  • Appendicectomy eradicates the infectious focus, while antimicrobials mitigate septic complications.