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Hypothyroidism in Thyroid Hemiagenesis: A Case Report.

Rakesh Kumar Shah1, Gagan Bohara2, Fnu Juveria3

  • 1Internal Medicine, Kathmandu Medical College and Teaching Hospital, Kathmandu, NPL.

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|April 25, 2022
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Summary

Thyroid hemiagenesis, a rare thyroid development issue, can present with hypothyroidism, not just hyperthyroidism. This case highlights a 72-year-old woman with congenital thyroid hemiagenesis and lifelong hypothyroidism.

Keywords:
anti-tpo antibodyautoimmunityhypothyroidismthyroid developmentthyroid hemiagenesis

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Area of Science:

  • Endocrinology
  • Developmental Biology
  • Medical Case Reports

Background:

  • Thyroid hemiagenesis is a rare congenital anomaly characterized by the unilateral absence of a thyroid lobe.
  • It is more prevalent in females and often involves the left lobe and thyroid isthmus.
  • While frequently associated with hyperthyroidism, it can also present with hypothyroidism.

Observation:

  • This report details a 72-year-old female diagnosed with hypothyroidism 25 years prior.
  • Neck ultrasound revealed the absence of the left thyroid lobe and isthmus.
  • Laboratory results indicated controlled hypothyroidism on levothyroxine therapy.

Findings:

  • The patient was diagnosed with congenital thyroid hemiagenesis associated with hypothyroidism.
  • Thyroid hemiagenesis can be an incidental finding presenting later in life.
  • Patients with thyroid hemiagenesis may have reduced thyroid hormone reserves, increasing hypothyroidism risk.

Implications:

  • This case expands the clinical spectrum of thyroid hemiagenesis presentation.
  • It underscores the importance of considering hypothyroidism in patients with thyroid hemiagenesis.
  • Early diagnosis and management are crucial for patients with thyroid hemiagenesis and associated thyroid dysfunction.