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An Improbable Thromboembolic Manifestation of COVID-19: A Case Report
Fátima Costa1, Luís Nogueira1, Salomé Marques1
1Internal Medicine, Centro Hospitalar Tâmega e Sousa, Penafiel, PRT.
Insights
This case highlights a rare instance of mesenteric artery thrombosis in a COVID-19 patient presenting with gastrointestinal symptoms. Early recognition of thromboembolic events is crucial for managing severe coronavirus disease 2019.
Area of Science:
- Vascular Medicine
- Infectious Diseases
- Gastroenterology
Background:
- Coronavirus disease 2019 (COVID-19) is increasingly recognized as a multisystem inflammatory condition.
- Thromboembolic complications, including deep venous thrombosis, pulmonary embolism, and stroke, are reported with higher frequency in COVID-19 patients.
- Gastrointestinal manifestations can occur in COVID-19, potentially complicating diagnosis.
Observation:
- A 75-year-old female with COVID-19 presented with progressive diffuse abdominal pain, diarrhea, and vomiting.
- Abdominal computed tomography revealed evidence of mesenteric artery thrombosis, a rare but life-threatening complication.
- The patient's gastrointestinal symptoms initially masked the severity of the underlying vascular event.
Findings:
- Mesenteric artery thrombosis is an uncommon but critical thromboembolic complication associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
- Gastrointestinal symptoms in COVID-19 patients can obscure the diagnosis of abdominal thromboembolic events.
- Prompt diagnosis and management of mesenteric artery thrombosis are essential for patient survival.
Implications:
- Clinicians should maintain a high index of suspicion for abdominal thromboembolic events in COVID-19 patients presenting with gastrointestinal symptoms.
- Differential diagnosis in COVID-19 should include vascular complications beyond respiratory manifestations.
- Early identification of mesenteric artery thrombosis can significantly improve patient outcomes in the context of SARS-CoV-2 infection.
Abstract:
The coronavirus disease 2019 (COVID-19) disease is a multisystem disease and recent studies have shown an increase in reported thromboembolic complications as deep venous thrombosis, pulmonary embolism (PE), stroke, and less frequently mesenteric artery thrombosis. We present a case of a 75-year-old woman, COVID-19 positive with five days of evolution, who was admitted to the emergency room due to diffuse abdominal pain with several days of progression, along with diarrhea and biliary vomit. Abdominal computed tomography presented images of subtraction of the lumen of the upper mesenteric artery. With the reported clinical case the authors intend to clarify the importance of differential diagnosis in patients with a typical severe acute respiratory syndrome coronavirus 2 (SARS CoV2) infection presentation. The gastrointestinal symptoms of SARS CoV2 infection can mask a more severe condition, so a high index suspicion for abdominal thromboembolic events is required once this complication may threaten patient's life.
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