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Ischemic retinal events after COVID-19 vaccination
Aaron Zachariah Priluck1, Jose Fernando Arevalo1, Ravi Rashmikant Pandit1
1Wilmer Eye Institute, Johns Hopkins, 1800 Orleans St, Baltimore, MD, 21287, USA.
American Journal of Ophthalmology Case Reports
|April 25, 2022
Summary
Two patients experienced ischemic retinal events shortly after receiving COVID-19 vaccines (Moderna and Johnson & Johnson/Janssen). This study highlights potential ocular side effects following vaccination, warranting further investigation.
Area of Science:
- Ophthalmology
- Vaccinology
- Immunology
Background:
- The safety profile of COVID-19 vaccines is continually evolving.
- Concerns regarding pro-thrombotic events have been raised, particularly with adenovirus vector vaccines.
Observation:
- A 57-year-old female developed branch retinal vein occlusion after Moderna vaccination.
- A 20-year-old female experienced acute macular neuroretinopathy after Johnson & Johnson/Janssen vaccination.
Findings:
- These cases represent the first reported instances of isolated ischemic retinal events post-COVID-19 vaccination.
- A transient pro-thrombotic retinal environment may occur following vaccination.
Implications:
- The immunologic response to COVID-19 vaccines, potentially inducing a pro-thrombotic state, may precipitate ischemic retinal events.
- Comprehensive ophthalmologic evaluation is recommended for patients presenting with ocular symptoms after COVID-19 vaccination.
