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Updated: Sep 25, 2025

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
A blistering eruption of the head and neck in an 18-year-old
Irene Timoney1, Emma Porter1, Niamh Leonard2
1Department of Dermatology, University Hospital Limerick, University of Limerick Hospitals Group, Dooradoyle, Limerick, Ireland.
Abstract:
An 18-year-old presented with an atypical blistering eruption. Direct immunofluorescence microscopy of perilesional skin showed strong linear deposition of IgG and C3 at the dermoepidermal junction. Her presentation was unusual and posed a diagnostic challenge, as this condition is very rare in this age group.
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