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Glutathione-Responsive Pyraclostrobin-Loaded Polyurea Microcapsules for Their Intelligent Controlled Release
Jian Wang1, Rong Wang1, Zefeng Shi1
1Shanghai Engineering Research Center of Green Energy Chemical Engineering, College of Chemistry and Materials Science, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, P. R. China.
Journal of Agricultural and Food Chemistry
|April 25, 2022
Summary
New glutathione-responsive polyurea microcapsules enhance pesticide delivery. This intelligent controlled release technology improves pyraclostrobin efficacy against Fusarium graminearum while reducing environmental impact.
Area of Science:
- Materials Science
- Agricultural Chemistry
- Environmental Science
Background:
- Stimuli-responsive pesticide formulations offer improved efficacy and reduced environmental pollution.
- Controlled release systems are key to optimizing pesticide performance.
Purpose of the Study:
- To develop glutathione-responsive polyurea microcapsules (PU-MCs) for controlled pyraclostrobin release.
- To evaluate the properties and efficacy of these novel microcapsules.
Main Methods:
- Interface polymerization was used to synthesize pyraclostrobin-loaded PU-MCs.
- Characterization included morphology, particle size, thermal stability, and rheological properties.
- Wettability on wheat leaves and in vitro release kinetics were assessed.
Main Results:
- Spherical PU-MCs (480 nm) with good thermal stability and rheological properties were obtained.
- Enhanced wettability on wheat leaves improved pesticide retention and utilization.
- Controlled pyraclostrobin release was directly proportional to glutathione (GSH) concentration via Fickian diffusion.
- Efficacy against Fusarium graminearum correlated positively with GSH levels.
Conclusions:
- Glutathione-responsive PU-MCs provide a promising platform for controlled pesticide delivery.
- This technology enhances pyraclostrobin efficacy and offers a foundation for agricultural applications.
- Further field experiments are warranted to validate performance in real-world conditions.
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