Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

1.0K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
1.0K
Liver Physiology01:30

Liver Physiology

1.4K
The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
1.4K
Liver Regeneration01:24

Liver Regeneration

3.4K
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
3.4K
Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

212
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
212

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Social determinants of vaccine hesitancy among the Lebanese parents: A cross-sectional Study.

PloS one·2026
Same author

A retrospective cross-sectional study on newborn screening and prevalence of disorders among UAE population.

Frontiers in pediatrics·2026
Same author

Swiss obesity clinical practice guidance.

Swiss medical weekly·2026
Same author

An extra virgin olive oil diet impairs glycemic control, but mitigates high-fat diet-induced inflammation compared to coconut oil in mice.

Frontiers in nutrition·2026
Same author

Diabetes mellitus complications and their association with patient-reported outcome measures: a longitudinal study of the SwissDiab cohort.

Diabetes research and clinical practice·2026
Same author

Social determinants of vaccine hesitancy among the Lebanese parents: A cross-sectional Study.

PloS one·2026

Related Experiment Video

Updated: Sep 25, 2025

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
08:41

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Published on: March 24, 2023

1.3K

Liver, NAFLD and COVID-19.

Carlotta Hoffmann1, Philipp A Gerber2, Claudia Cavelti-Weder2

  • 1University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany, Department of Internal Medicine III, Dresden, Germany.

Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme
|April 25, 2022
PubMed
Summary

This review details the two-way link between COVID-19 and liver health, highlighting increased risks for individuals with liver disease and exploring impacts on non-alcoholic fatty liver disease (NAFLD).

More Related Videos

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
07:03

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

1.1K
A Model of Experimental Steatosis In Vitro: Hepatocyte Cell Culture in Lipid Overload-Conditioned Medium
08:35

A Model of Experimental Steatosis In Vitro: Hepatocyte Cell Culture in Lipid Overload-Conditioned Medium

Published on: May 18, 2021

6.8K

Related Experiment Videos

Last Updated: Sep 25, 2025

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
08:41

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Published on: March 24, 2023

1.3K
Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
07:03

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

1.1K
A Model of Experimental Steatosis In Vitro: Hepatocyte Cell Culture in Lipid Overload-Conditioned Medium
08:35

A Model of Experimental Steatosis In Vitro: Hepatocyte Cell Culture in Lipid Overload-Conditioned Medium

Published on: May 18, 2021

6.8K

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Internal Medicine

Background:

  • Coronavirus disease 2019 (COVID-19) presents with diverse clinical manifestations, including liver function abnormalities.
  • Individuals with pre-existing liver diseases face elevated risks for severe COVID-19 outcomes.
  • A significant bidirectional relationship exists between COVID-19 and liver health.

Purpose of the Study:

  • To review epidemiologic evidence on the COVID-19 and liver disease relationship.
  • To elucidate mechanisms of COVID-19-induced liver injury.
  • To examine the impact of COVID-19 on non-alcoholic or metabolic-associated fatty liver disease (NAFLD/MAFLD) and vice versa.

Main Methods:

  • Systematic review of epidemiologic data.
  • Analysis of histologic findings in COVID-19 patients with liver involvement.
  • Review of mechanistic studies on direct and indirect pathways of liver injury.
  • Focused analysis on NAFLD/MAFLD and its interaction with COVID-19.

Main Results:

  • The review synthesizes evidence on the complex interplay between COVID-19 infection and liver function/disease.
  • Common histologic findings and key mechanisms contributing to COVID-19-related liver injury are detailed.
  • The impact of COVID-19 on NAFLD/MAFLD progression and the exacerbating effect of NAFLD/MAFLD on COVID-19 severity are discussed.

Conclusions:

  • COVID-19 and liver diseases share a significant bidirectional relationship, influencing disease severity and outcomes.
  • Understanding these interactions is crucial for managing patients with both conditions.
  • The long-term effects of the pandemic on NAFLD development and management warrant further investigation.