Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Sep 25, 2025

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

11.7K

Applications of triplex DNA nanostructures in sensor development.

Pei-Ying Lin1, Rong Chi2, Yu-Ling Wu1

  • 1BioAnalytical Chemistry and Nanobiomedicine Laboratory, Department of Biochemical Science and Technology, National Taiwan University, Taipei, 10617, Taiwan.

Analytical and Bioanalytical Chemistry
|April 26, 2022
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beyond Single-Active Sites: The Emergence of High-Entropy Perovskites in Energy and Environment Catalysis.

ChemSusChem·2026
Same author

Correction to "Prominent Vascularization Capacity of Mesenchymal Stem Cells in Collagen-Gold Nanocomposites".

ACS applied materials & interfaces·2026
Same author

Invisible plastic release from overlooked usage practices in microwaved food packaging.

Food chemistry·2026
Same author

A Risk Model Using Refined Disease Risk Index and 1-Month NK-Cell Count for Relapse in Children and Adults with T-ALL/LBL After Myeloablative Umbilical Cord Blood Transplantation.

Blood and lymphatic cancer : targets and therapy·2026
Same author

Corrigendum to "Functional engineered mesenchymal stem cells with fibronectin‑gold composite coated catheters for vascular tissue regeneration" [Nanomed: Nanotechnol Biol Med 14 (2018) 699-711].

Nanomedicine : nanotechnology, biology, and medicine·2026
Same author

Diagnosis of Endometriosis: Dual-Amplification Strategy Driven by Copper Nanoclusters.

Analytical chemistry·2026

DNA triplex nanostructures offer versatile applications in biosensing and drug delivery. This review highlights their use in developing novel biosensors for detecting nucleic acids and other molecules.

Area of Science:

  • Biotechnology and Nanotechnology
  • Molecular Biology
  • Biosensor Development

Background:

  • Triplex DNA nanostructures exhibit unique nanoparticle-like organization and characteristics.
  • They are increasingly recognized for their versatile utility in science and technology.
  • Applications span clinical diagnostics, disease detection, and stimuli-responsive drug delivery.

Purpose of the Study:

  • To review the utilization of DNA triplexes in the development of biosensors.
  • To explore strategies for sensing nucleic acids, pH, protein activity, ions, and molecules using DNA triplexes.
  • To provide an outlook on potential applications of triplex DNA nanoswitches.

Main Methods:

  • Literature review focusing on DNA triplex-based biosensor development.
Keywords:
AptasensorsTriplex DNA nanostructureTriplex-helix molecular switchpH dependence

More Related Videos

A Polyaniline-based Sensor of Nucleic Acids
07:58

A Polyaniline-based Sensor of Nucleic Acids

Published on: November 1, 2016

8.2K
Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging
04:33

Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging

Published on: December 8, 2023

1.0K

Related Experiment Videos

Last Updated: Sep 25, 2025

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

11.7K
A Polyaniline-based Sensor of Nucleic Acids
07:58

A Polyaniline-based Sensor of Nucleic Acids

Published on: November 1, 2016

8.2K
Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging
04:33

Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging

Published on: December 8, 2023

1.0K
  • Analysis of sensing strategies for various analytes including nucleic acids, ions, and biomolecules.
  • Examination of DNA triplex nanoswitch applications.

    • Main Results:

    • DNA triplexes serve as a foundation for advanced biosensor designs.
    • Effective strategies exist for detecting a range of targets using DNA triplexes.
    • Triplex DNA nanoswitches show promise for future applications.

    Conclusions:

    • DNA triplex nanostructures are powerful tools for biosensing and diagnostics.
    • Further development of triplex DNA nanoswitches could lead to innovative applications.
    • This review consolidates current knowledge and future directions in the field.