Related Experiment Video
Updated: Sep 25, 2025

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Mycotic aneurysm
Bryan J Neth1, Salomon Cohen Cohen2, Jorge Trejo-Lopez1
1Mayo Clinic Rochester, Rochester, Minnesota, USA.
Abstract:
Angioinvasive fungal infections of the cerebral vasculature often lead to significant morbidity and mortality. High clinical suspicion and early antifungal therapy could improve outcomes. We describe the fatal case of a patient with a rapidly enlarging cavernous carotid aneurysm due to angioinvasive fungus. This case highlights the challenges in diagnosis and management of this condition.
Insights
Angioinvasive fungal infections can be fatal, affecting cerebral blood vessels. Early diagnosis and treatment are crucial for improving patient outcomes in these challenging cases.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Surgery
Background:
- Cerebral vascular infections pose significant risks.
- Angioinvasive fungal infections are particularly dangerous, leading to high morbidity and mortality.
- Early detection and treatment are key to improving outcomes.
Observation:
- A patient presented with a rapidly enlarging cavernous carotid aneurysm.
- The aneurysm was caused by an angioinvasive fungal infection.
- The patient's case was ultimately fatal.
Findings:
- Angioinvasive fungal infections of the brain present diagnostic and management challenges.
- Rapidly enlarging aneurysms can be a sign of such infections.
- This condition requires high clinical suspicion for timely intervention.
Implications:
- Highlights the need for increased awareness of fungal vascular infections.
- Emphasizes the importance of prompt diagnosis and antifungal therapy.
- Suggests potential for improved management strategies with further research.
Related Concept Videos
Aneurysm I: Introduction
Aneurysm III: Interprofessional Care
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm IV: Nursing Management
Fungal Group Zygomycota
Anastomoses
Anastomoses can be formed at arterial, venous, and lymphatic vessels.
Arterial Anastomosis: These occur between arteries. They...

