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Related Experiment Video

Updated: Sep 25, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Update on migraine management.

¹Ms. Medicine, Cincinnati, Ohio.

Menopause (New York, N.Y.)

|April 26, 2022

Summary

Migraine is common in women, causing disability but often missed. New targeted therapies, focusing on calcitonin gene-related peptide, offer improved management options for healthcare professionals.

Area of Science:

Neurology
Women's Health

Background:

Migraine is a prevalent neurological disorder disproportionately affecting women, leading to significant disability.
Despite its prevalence, migraine remains underdiagnosed and undertreated in many populations.
Advances in understanding migraine pathophysiology, particularly the role of calcitonin gene-related peptide (CGRP), have spurred therapeutic innovation.

Purpose of the Study:

To highlight the importance of accurate migraine diagnosis in women.
To emphasize a stepwise approach for managing acute and chronic migraine.
To inform healthcare professionals about new targeted migraine therapies.

Main Methods:

Review of current understanding of migraine pathophysiology.
Analysis of diagnostic criteria for migraine.

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Evaluation of biobehavioral and pharmacologic management strategies.

Inclusion of recently approved targeted therapies.

Main Results:

New targeted therapies based on CGRP inhibition are available.
A structured, stepwise approach to migraine management is recommended.
Familiarity with diagnostic criteria and treatment options is crucial for clinicians.

Conclusions:

Healthcare professionals must be knowledgeable about migraine diagnosis and management in women.
Integrating biobehavioral and pharmacologic treatments, including novel therapies, is key.
Addressing underdiagnosis and undertreatment can improve patient outcomes and reduce disability.