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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
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Anxiety and Depression Following Aortic Valve Replacement
Zachary K Wegermann1,2, Michael J Mack3, Suzanne V Arnold4
1Division of Cardiology Department of Medicine Duke University Health System Durham NC.
Journal of the American Heart Association
|April 26, 2022
Summary
Transcatheter aortic valve replacement (TAVR) is associated with a lower risk of anxiety and/or depression compared to surgical aortic valve replacement (SAVR), especially within the first six months post-procedure.
Area of Science:
- Cardiology
- Psychiatry
- Health Services Research
Background:
- Anxiety and/or depression are significant concerns following aortic valve replacement (AVR).
- Identifying patients at risk and mitigating factors is crucial for improving outcomes.
- Previous studies have not fully elucidated the comparative psychological impact of different AVR approaches.
Purpose of the Study:
- To identify patients vulnerable to anxiety and/or depression after AVR.
- To evaluate factors that may mitigate the risk of postoperative anxiety and/or depression.
- To compare the risk of anxiety and/or depression between transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR).
Main Methods:
- Retrospective cohort study using a claims database of 18,990 patients aged ≥55 years.
- Analysis of pre- and post-AVR data from January 2013 to December 2018.
- Risk-adjusted logistic regression and Cox proportional hazards models were used to compare anxiety and/or depression rates at 3 months, 6 months, and 1 year post-AVR.
Main Results:
- Patients undergoing SAVR had a higher relative risk of anxiety and/or depression at 3 and 6 months post-AVR compared to TAVR.
- This risk difference narrowed by 12 months post-AVR.
- The association was more pronounced in patients discharged home and those without operative complications.
Conclusions:
- TAVR is associated with a reduced risk of new-onset anxiety and/or depression compared to SAVR.
- This risk reduction is particularly evident in the initial 3 to 6 months following treatment.
- Discharge location and the presence of operative complications influence postoperative psychological outcomes.
Keywords:
aortic valve replacementpostoperative anxietypostoperative depressionsurgical aortic valve replacementtranscatheter aortic valve replacementMore Related Videos
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