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A simple neural vector space model for medical concept normalization using concept embeddings.

Dongfang Xu1, Timothy Miller1

  • 1Computational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Harvard Medical School Boston, MA, USA.

Journal of Biomedical Informatics
|April 26, 2022
PubMed
Summary
This summary is machine-generated.

We developed a simple neural model for medical concept normalization (MCN) that directly links text mentions to ontology concepts. This model achieves state-of-the-art results on clinical datasets and simplifies MCN application in new settings.

Keywords:
Deep LearningMedical Concept NormalizationNatural Language ProcessingNormalized Temperature-scaled SoftmaxVector Space Model

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Area of Science:

  • Natural Language Processing
  • Medical Informatics
  • Machine Learning

Background:

  • Medical Concept Normalization (MCN) unifies diverse textual references to identical concepts.
  • Existing MCN methods often involve complex pipelines and hand-crafted rules.

Purpose of the Study:

  • To introduce a simple, direct neural model for Medical Concept Normalization (MCN).
  • To achieve competitive and state-of-the-art performance on clinical MCN tasks.

Main Methods:

  • A neural MCN model utilizing an encoder (SAPBERT) and a normalized temperature-scaled softmax (NT-softmax) layer.
  • Directly predicting concepts from mentions, bypassing complex preprocessing.
  • Initializing NT-softmax weights with pre-computed concept embeddings.

Main Results:

  • Achieved competitive performance on the ShARe/CLEF 2013 dataset.
  • Established a new state-of-the-art on the 2019 n2c2/OHNLP MCN task.
  • Demonstrated the superiority of NT-softmax over conventional softmax for MCN.

Conclusions:

  • The proposed simple neural MCN model offers a more effective and straightforward approach.
  • The NT-softmax layer and specific initialization strategies enhance MCN performance.
  • Future MCN research may need to address the challenge of unseen concepts.