Reintervention rate in glaucoma filtering surgery: A systematic review and meta-analysis

Area of Science:

• Ophthalmology
• Surgical Outcomes
• Glaucoma Management

Background:

• Reintervention rates after glaucoma surgery significantly impact patients, surgeons, and healthcare systems.
• Limited research exists on the reintervention rates for various glaucoma filtering procedures.

Purpose of the Study:

• To systematically review and meta-analyze reintervention rates following glaucoma filtering surgery.
• To identify specific surgical devices associated with differing reintervention rates.

Main Methods:

• A systematic search of PubMed, Medline, and Embase databases was conducted for prospective studies.
• Studies included were required to have a minimum follow-up of 12 months.
• Primary outcome was the total reintervention rate; secondary outcomes included manipulation rates, reinterventions for intraocular pressure (IOP) control and complications.

Main Results:

• Ninety-three studies encompassing 8345 eyes were analyzed.
• The overall reintervention rate was 1.84%.
• Baerveldt (0.53%) and Preserflo (0.60%) devices had lower reintervention rates, while Xen (4.26%) had a higher rate.

Conclusions:

• Glaucoma filtering surgery reintervention rates differ by device, with Baerveldt and Preserflo showing lower rates and Xen a higher rate.
• No demographic, clinical, or surgical variables were directly associated with reintervention outcomes.