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Related Experiment Video

Updated: Sep 25, 2025

Facilitating the Analysis of Immunological Data with Visual Analytic Techniques

Facilitating the Analysis of Immunological Data with Visual Analytic Techniques

Published on: January 2, 2011

ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS.

Jonathon Fleming¹, Skylar W Marvel¹, Stacy Supak²

¹Bioinformatics Research Center, Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.

Journal of Exposure Science & Environmental Epidemiology

|April 27, 2022

Summary

The ToxPi*GIS Toolkit integrates Toxicological Prioritization Index (ToxPi) profiles with ArcGIS, enabling interactive geospatial analysis and public sharing of complex environmental health data.

Keywords:

Data integration Geographic information systems Visual analytics

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Area of Science:

Environmental Health Sciences
Geographic Information Systems (GIS)
Toxicology

Background:

Integrating multi-factor geographic data for comprehensive analysis is challenging.
Interactive visualization is crucial for public sharing and GIS analysis.
The Toxicological Prioritization Index (ToxPi) framework visualizes integrated data, but lacks ArcGIS integration.

Purpose of the Study:

Introduce the ToxPi*GIS Toolkit for creating, viewing, sharing, and analyzing interactive ToxPi profiles within ArcGIS.
Enable novel GIS analyses and provide a public avenue for geospatial results.
Facilitate the integration of ToxPi profiles into existing GIS workflows.

Main Methods:

Developed a software suite including an ArcGIS Toolbox (ToxPiToolbox.tbx) for drawing location-specific ToxPi profiles.
Created modular Python scripts for command-line creation of ToxPi feature layers.
Provided Python routines for data manipulation and preprocessing, with documented workflows for users of all skill levels.

Main Results:

Map visualizations with ToxPi profiles can be shared via public URLs, accessible without ArcGIS Pro.
Novice ArcGIS Pro users can create custom maps; advanced users benefit from customization options.
Demonstrated ToxPi feature layer creation using COVID-19 data to analyze pandemic vulnerability drivers across US counties.

Conclusions:

Integrating ToxPi profiles with ArcGIS opens new possibilities for geospatial analysis, visualization, and public data sharing.
This integration supports decision-making for public health issues like disease prevention and environmental health.
Ongoing development of the ToxPi*GIS Toolkit (www.toxpi.org) aims to advance scientific research across various fields.