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Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks

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A flexible robust model for blood supply chain network design problem.

Soheyl Khalilpourazari^1,2, Hossein Hashemi Doulabi^1,2

¹Department of Mechanical, Industrial & Aerospace Engineering, Concordia University, Montreal, Canada.

Annals of Operations Research

|April 27, 2022

Summary

This study presents a robust model for emergency blood supply chains, optimizing logistics during the COVID-19 pandemic. The model effectively handles uncertainties, reducing costs and delivery times for critical blood products.

Keywords:

Blood supply chain Chance constraint Flexible programming Flexible robust optimization

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Published on: August 21, 2020

Area of Science:

Operations Research
Supply Chain Management
Public Health Emergencies

Background:

COVID-19 pandemic caused significant disruptions to blood donation and supply chains globally.
Effective emergency blood supply chain design is crucial for managing blood shortages during crises.

Purpose of the Study:

To develop a novel multi-objective Transportation-Location-Inventory-Routing (TLIR) formulation for emergency blood supply chain network design.
To address strategic, operational, and tactical decisions under network disruptions and blood shelf-life constraints.
To propose uncertain models for risk-averse and robust solutions in dynamic environments.

Main Methods:

Development of a multi-objective TLIR mathematical formulation.
Introduction of two flexible uncertain models to handle parameter variability.
Application of the proposed formulations in a comprehensive case study with extensive worst-case analyses.

Main Results:

The robust model demonstrated superior efficiency in managing uncertainties compared to other approaches.
The proposed model significantly reduced costs and delivery times for blood products.
Worst-case analyses confirmed the robustness and reliability of the obtained solutions.

Conclusions:

The developed robust model provides an effective framework for designing resilient emergency blood supply chains.
Managerial insights are offered to enhance the overall effectiveness and efficiency of blood supply chain operations during emergencies.