Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

PathoFact 2.0: an integrative pipeline for the prediction of antimicrobial resistance genes, virulence factors, toxins and toxin-associated proteins, and biosynthetic gene clusters in metagenomes.

GigaScience·2026

Same author

Integrative analysis of the mouse cecal microbiome across diet, age, and weight in the diverse BXD population.

Microbiome·2026

Same author

High-resolution multi-omics enhances prediction and detection of smORF-encoded proteins in the human gut microbiome.

Nature communications·2026

Same author

Multi-meta-omics reveal distinct microbial genomic profiles and metabolic dysregulation in non-celiac gluten sensitivity.

mSphere·2026

Same author

Cross-domain interactions confer stability to benthic biofilms in proglacial streams.

Frontiers in microbiomes·2026

Same author

Phylum-wide propionate degradation and its potential connection to poly-gamma-glutamate biosynthesis in Candidatus Cloacimonadota phylum.

The ISME journal·2026

Same journal

A computational method to design broad-spectrum T cell-inducing vaccines applied to Betacoronaviruses.

Cell reports methods·2026

Same journal

MalDeepSeq panel: A targeted ultra-deep sequencing approach to trace drug resistance markers in Plasmodium falciparum.

Cell reports methods·2026

Same journal

Induced pluripotent stem cell-derived macrophages enable broad modeling of human inflammasome signaling.

Cell reports methods·2026

Same journal

Rapid discovery of cell-surface glycosylation regulators using a lectin-based magnetic CRISPR screen.

Cell reports methods·2026

Same journal

A real-time FRET ubiquitin transfer assay for quantitative characterization of ternary complexes in targeted protein degradation.

Cell reports methods·2026

Same journal

A high-throughput, end-to-end pipeline for extracellular miRNA biomarker discovery from human biofluids.

Cell reports methods·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Sep 25, 2025

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing

Published on: March 19, 2018

Toward hypothesis-driven, personalized microbiome screening.

Catherine Sedrani¹, Paul Wilmes^1,2

¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.

Cell Reports Methods

|April 27, 2022

Summary

This summary is machine-generated.

The human gut microbiome

More Related Videos

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease

Published on: January 10, 2025

Related Experiment Videos

Last Updated: Sep 25, 2025

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing

Published on: March 19, 2018

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease

Published on: January 10, 2025

Area of Science:

Microbiome research
Genomics
Human health

Background:

The human gut microbiome plays a vital role in health and disease.
Significant individual variation exists at the strain level within the gut microbiome.
Different strains possess distinct genetic and functional capabilities.

Purpose of the Study:

To advance genome-based screening methods for microbiome analysis.
To enable a deeper understanding of the human gut microbiome at the strain level.
To investigate the functional roles of specific microbial strains in human health.

Main Methods:

Development of novel genome-based screening techniques.
Analysis of microbial genomes to identify functional variations.
Comparative genomics for strain-level characterization.

Main Results:

Demonstrated progress in genome-based microbiome screening.
Established a foundation for strain-level functional analysis.
Highlighted the importance of strain variation in microbiome function.

Conclusions:

Genome-based screening is key to understanding microbiome function.
Strain-level analysis offers personalized insights into health and disease.
Further research can elucidate the precise roles of gut microbial strains.