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Related Experiment Video

Updated: Sep 25, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Ayurvedic formulations: Potential COVID-19 therapeutics?

Anees Ahmed Mahaboob Ali1, Andrea Bugarcic2, Nenad Naumovski3,4

  • 1Centre for Research in Therapeutic Solutions, Faculty of Science and Technology, University of Canberra, Canberra, Australia.

Phytomedicine Plus : International Journal of Phytotherapy and Phytopharmacology
|April 27, 2022
PubMed
Summary

Ayurvedic treatments show promise for COVID-19, with studies indicating faster recovery times. Further research into their prophylactic and therapeutic properties is warranted for managing SARS-CoV-2 infection.

Keywords:
AntiviralsAyurvedic formulationsCOVID-19Clinical trialsIn silico molecular docking

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Area of Science:

  • Integrative Medicine
  • Pharmacology
  • Infectious Diseases

Background:

  • Limited treatment options for COVID-19 (caused by SARS-CoV-2) exist, with Molnupiravir and Paxlovid recently approved in some regions.
  • Ayurvedic medicine has a history of using herbal extracts for respiratory ailments with minimal side effects.
  • Current research is exploring Ayurvedic formulations as potential COVID-19 treatments.

Purpose of the Study:

  • To review existing research on Ayurvedic formulations for COVID-19 treatment.
  • To present the current state of knowledge by integrating findings from various study types.
  • To identify commonly used formulations and their therapeutic potential.

Main Methods:

  • Conducted a literature search for in silico, in vitro, in vivo, and clinical studies.
  • Focused on Ayurvedic formulations investigated for COVID-19 treatment.
  • Integrated information across all study systems to synthesize current knowledge.

Main Results:

  • 20 in silico studies examined phytoconstituent interactions with SARS-CoV-2.
  • 5 preclinical studies investigated the ability of formulations to inhibit viral functions.
  • 51 clinical trials were completed, with data from 17 showing shorter recovery periods for COVID-19 patients using Ayurvedic treatments.

Conclusions:

  • Commonly used Ayurvedic treatments may possess prophylactic and/or therapeutic properties for SARS-CoV-2 infection.
  • Further investigation into synergistic effects and antiviral activities of individual phytoconstituents is recommended.
  • Assessing combinations of phytoconstituents in Ayurvedic treatments is of particular interest.