Ileal gastrointestinal stromal tumor causing mesenteric gangrene
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Updated: Sep 25, 2025
Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Hazem Beji1, Mahdi Bouassida1, Slim Zribi1
1Department of General Surgery Hospital Mohamed Taher Maamouri Nabeul Tunisia.
Abstract:
To our knowledge, this is one of the rare literature reports of an ileal GIST complicated with mesenteric gangrene. We reported successful surgical treatment. Infection of GIST is an extremely rare complication that should be treated with no delays to avoid rupture and peritonitis.
Insights
This study reports a rare case of ileal gastrointestinal stromal tumor (GIST) with mesenteric gangrene. Successful surgical treatment was achieved, highlighting the importance of prompt intervention for GIST infections to prevent severe complications.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms.
- Ileal GISTs represent a subset of these tumors, with unique clinical presentations.
- Complications of GISTs, such as infection and gangrene, are exceptionally infrequent.
Observation:
- A rare case of an ileal GIST complicated by mesenteric gangrene is presented.
- The patient presented with symptoms indicative of a severe intra-abdominal process.
- Diagnostic imaging revealed features consistent with GIST and associated ischemic changes.
Findings:
- Histopathological examination confirmed the diagnosis of GIST.
- Mesenteric gangrene was identified as a direct complication of the ileal GIST.
- The GIST was successfully treated with surgical resection.
Implications:
- This case underscores the potential for GISTs to cause severe, life-threatening complications like mesenteric gangrene.
- Prompt diagnosis and surgical intervention are crucial for managing infected GISTs and preventing peritonitis.
- Further research into the pathogenesis of GIST complications may improve patient outcomes.
