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Author Spotlight: A Novel Protocol for Intracameral Injections to Enhance Precision in Rodent Ophthalmology
Published on: May 31, 2024
Management of intraorbital infections in the pediatric emergency department
Michael Sorotzky1, Keren Shahar-Nissan2, Avram R Shack1
1Department of Pediatrics, Wilf Children's Hospital, Shaare Zedek Medical Center, Jerusalem, Israel.
Insights
Pediatric intraorbital infections are treated based on clinical judgment, not imaging. Three or more high-risk symptoms may increase the likelihood of surgical intervention for these infections.
Area of Science:
- Ophthalmology
- Pediatric Emergency Medicine
- Infectious Diseases
Background:
- Orbital cellulitis poses significant risks, requiring prompt diagnosis and treatment.
- Current literature lacks clear guidelines for emergency department management of intraorbital infections.
Purpose of the Study:
- To investigate the decision-making process for emergent imaging and surgical intervention in pediatric intraorbital infections.
- To identify factors influencing management decisions in intraorbital infections.
Main Methods:
- Retrospective cohort study of pediatric patients with intraorbital infections from 2010-2020.
- Analysis of computerized tomography (CT) timing, surgical vs. conservative management, and complication rates.
- Evaluation of clinical symptoms, duration of complaints, and CT findings in relation to management.
Main Results:
- Seventy out of 95 patients underwent CT within 24 hours; 21 of these had surgical management.
- Sixteen patients were treated based on clinical findings without imaging.
- No significant differences in management based on presenting symptoms, duration, or CT severity were found.
- Three or more high-risk symptoms were associated with a higher likelihood of surgical intervention (OR 1.73).
Conclusions:
- Treatment decisions for intraorbital infections are primarily driven by clinical assessment of disease severity.
- Radiologic findings did not significantly influence management choices in this cohort.
- Further interdisciplinary research is needed to establish optimal management protocols.
Abstract:
Intraorbital infections may lead to severe complications, necessitating rapid diagnosis and intervention. The decision process regarding the need for emergent imaging and possible surgical intervention is unclear in the literature. This retrospective cohort study included two major pediatric emergency departments in Israel between 2010 and 2020. Patients arriving at the emergency department with an admission diagnosis of intraorbital infection and at least one high-risk symptom for orbital involvement were included in the study. The main outcome measures were the computerized tomography (CT) timing and results, whether the case was managed surgically or conservatively and whether the patient returned to the same hospital with significant complications. Ninety-five patients were included; 70 underwent a CT scan in the first 24 h, and of those 21 were managed surgically; 16 were treated based on clinical findings alone, with no imaging performed. When comparing groups based on management, we found no significant differences based on presenting symptoms, duration of complaints, or severity of CT findings. However, having three or more high-risk presenting symptoms was associated with a greater likelihood of surgical intervention (multivariate logistic regression p = 0.069, odds ratio 1.73, 95% confidence interval 0.96-3.11; one-way ANOVA and Fisher's exact test p < 0.05).
Conclusion:
The decision to treat intraorbital infections at our institutions appears to be based on clinical impression of disease severity rather than radiologic findings. This suggests a need for further interdisciplinary studies to clarify optimal management.
What Is Known:
• Orbital c ellulitis is associated with significant potential complications, necessitating rapid diagnosis and treatment. • Present literature provides insufficiently clear guidance on emergency department management.
What Is New:
• Consideration of all relevant factors (clinical features, laboratory findings, timing of imaging, and conservative vs. surgical management) in a single retrospective cohort. • Our findings suggest that decision-making in practice may be guided by clinical impression rather than imaging.
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