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Croup as a Previously Unrecognized Symptom of COVID-19 in Infants

Sevgi Dasdemir1, Mutlu Uysal Yazici2, Elif Gudeloglu3

  • 1From the Department of Pediatrics.

The Pediatric Infectious Disease Journal
|April 27, 2022
PubMed

Insights

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause croup in infants, a condition that has notably increased with the Omicron variant. This study identifies SARS-CoV-2 as the cause of croup in a pediatric case.

Area of Science:

  • Pediatrics
  • Virology
  • Infectious Diseases

Background:

  • Coronavirus disease 2019 (COVID-19) commonly presents with fever and cough in children.
  • Croup cases linked to COVID-19 have risen, particularly with the Omicron variant.
  • The specific viral agent in pediatric croup associated with COVID-19 requires further elucidation.

Purpose of the Study:

  • To identify the viral agent responsible for croup in an infant with COVID-19.
  • To highlight the association between severe acute respiratory syndrome coronavirus 2 and pediatric croup.

Main Methods:

  • Case presentation of an infant with croup.
  • Diagnostic testing to identify the viral etiology.

Main Results:

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the causative agent.
  • The infant presented with symptoms consistent with croup.

Conclusions:

  • SARS-CoV-2 can manifest as a cause of croup in infants.
  • The Omicron variant may be associated with an increased incidence of COVID-19-related croup in children.

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