Multiple fibroxanthosarcoma of bone

A case of multiple fibroxanthrosarcoma of bone is described. Clinically, the patient presented with multiple osteolytic lesions involving the skull, ribs, vertebral body, pelvic bones and proximal femur simulating multiple myeloma or metastatic carcinoma. The histologic features of the lesion fulfilled the criteria established for the recently delineated fibroxanthosarcoma. Three similar cases reported as multiple diffuse fibrosarcoma of bone are reviewed and the terminology for these lesions discussed.