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Poor Uptake of MMR Vaccine 1-year Post-Measles Outbreak: New York City and Israel

Michal Paret1, Rebecca Trillo2, Jennifer Lighter1

  • 1Department of Pediatrics, Division of Pediatric Infectious Diseases, New York University Grossman School of Medicine, New York, New York, USA.

Journal of the Pediatric Infectious Diseases Society
|April 28, 2022
PubMed

Insights

Measles outbreaks in New York and Israel disproportionately affected unvaccinated children. Many eligible children remained unimmunized post-outbreak, highlighting the need for better vaccination strategies and vitamin A awareness.

Area of Science:

  • Epidemiology
  • Pediatrics
  • Public Health

Background:

  • Large measles outbreaks occurred in Israel and New York City in 2018-2019.
  • Travel of unvaccinated children contributed to the spread between these communities.

Purpose of the Study:

  • To analyze measles cases and vaccination status in children tested during outbreaks in New York and Israel.
  • To evaluate the impact of measles, mumps, and rubella (MMR) vaccination on measles infection and outcomes.

Main Methods:

  • Retrospective chart review of children tested for measles between March 2018 and September 2019.
  • Analysis of vaccination records for measles, mumps, and rubella (MMR) at the time of testing and one year later.

Main Results:

  • 102 out of 264 (38.6%) children tested had confirmed measles.
  • Measles-positive children were significantly less likely to be vaccinated with MMR compared to measles-negative children at the time of testing (37% vs 65.4%).
  • Over 25% of children in both measles-positive and -negative groups remained unvaccinated for MMR one year after the outbreak.

Conclusions:

  • The majority of measles cases occurred in unvaccinated children eligible for the MMR vaccine.
  • A significant proportion of children, both infected and not infected with measles, remained unvaccinated one year post-outbreak.
  • Novel vaccination strategies and increased awareness of vitamin A's role are suggested.
Abstract

Keywords:
childrenmeaslesoutbreakvaccinationvitamin A

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