Imaging of the skin microvascularization using spatially depolarized dynamic speckle
Elise Colin1,2, Aurélien Plyer1,2, Muriel Golzio3
1Paris Saclay University, DTIS, ONERA, Palaiseau, France.
Significance:
We propose a technique devoted to real-time high-resolution imaging of skin microvascularization.
Aim:
The process utilizes the temporal variation of the spatially depolarized optical speckle field generated by moving red blood cells when illuminated with fully polarized coherent light.
Approach:
Polarimetric filtering prevents the contribution of surface scattering from reaching the camera and thus favors the detection of multiscattered photons from the deeper layers of the skin.
Results:
Full-field images reveal the microvasculature with a spatial resolution of 80 μm. The acquisition speed allows for real-time applications.
Conclusions:
We demonstrate the ability of this method to determine in 1 s a stable and reliable microvascular activity, enabling numerous clinical applications that require quantitative measurements.
