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Published on: February 10, 2023
Correlation of Clinical Class with Duplex Ultrasound Findings in Lower Limb Chronic Venous Disease
1Department of Thoracic and Cardiovascular Surgery, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
Insights
This study on chronic venous disease (CVD) found that advanced CEAP classifications (C3-C6) did not correlate with specific reflux patterns. Duplex ultrasonography is crucial for planning treatment in all CEAP categories, especially C0s-C1.
Area of Science:
- Vascular Surgery
- Medical Imaging
- Clinical Diagnostics
Background:
- Chronic venous disease (CVD) affects a significant portion of the population.
- Accurate classification and understanding of venous valve incompetence are essential for effective treatment.
- The Clinical, Etiological, Anatomical, and Pathophysiological (CEAP) classification system is widely used to stage CVD.
Purpose of the Study:
- To investigate the distribution of venous valve incompetence in patients with CVD.
- To correlate the findings of valve incompetence with the CEAP classification.
- To evaluate the utility of duplex ultrasonography in diagnosing and managing CVD.
Main Methods:
- A cohort of 1,386 limbs with suspected CVD were analyzed.
- Limbs were classified using the CEAP system.
- Duplex ultrasonography was performed to assess venous valve function and reflux patterns.
Main Results:
- Saphenous vein incompetence was prevalent, particularly in earlier CEAP stages (C0s-C1).
- The saphenofemoral junction (SFJ) was competent in a notable proportion of limbs with more advanced CEAP classifications (C2-C6).
- CEAP categories C3-C6 showed no significant correlation with saphenous vein reflux, SFJ reflux, deep vein reflux, or great saphenous vein (GSV) incompetence distribution.
Conclusions:
- Duplex ultrasonography is vital for treatment planning across all CEAP stages, especially C0s-C1.
- Flush ligation of the GSV may not always be necessary in CEAP C2-C6 patients with SFJ competence.
- The CEAP C3-C6 classification has limited predictive value for specific venous reflux patterns.
Background:
This study investigated the distribution of valve incompetence in patients with chronic venous disease (CVD) and its correlation with the clinical category of the clinical, etiological, anatomical, and pathophysiological (CEAP) classification.
Methods:
In total, 1,386 limbs with clinically suspected CVD were categorized according to the CEAP classification and consecutively underwent duplex ultrasonography between April 2017 and December 2020.
Results:
There were 362 limbs in male patients and 1,024 limbs in female patients. The limbs were classified as C0s-C1 (608 limbs, 43.8%), C2 (727 limbs, 52.5%), or C3-C6 (51 limbs, 3.7%). The prevalence of saphenous vein incompetence in CEAP C0s-C1 limbs was 43.6%. The saphenofemoral junction (SFJ) was competent in 37% of CEAP C2-C6 limbs. The CEAP C3-C6 category was not correlated with reflux patterns of the saphenous vein system (Cramer's V=0.07), incompetent SFJ (Cramer's V=0.07), deep vein reflux (Cramer's V=0.03), or the distribution of incompetent segments in the great saphenous vein (GSV) (Cramer's V=0.11).
Conclusion:
Duplex ultrasonography is necessary to formulate a proper treatment plan for limbs categorized as CEAP C0s-C1. The SFJ was competent in more than one-third of CEAP C2-C6 limbs with GSV reflux; as such, flush ligation of the GSV may be unnecessary in these patients. The CEAP C3-C6 category showed no correlations with reflux patterns of the saphenous vein system, SFJ reflux, deep vein reflux, or the distribution of incompetent segments in the GSV.
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